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Asynchronous Bilateral Achilles Tendon Rupture with Selective Androgen Receptor Modulators: A Case Report.
Heath P Gould1, Jessica B Hawken, Grant T Duvall
1Department of Orthopaedic Surgery, MedStar Union Memorial Hospital, Baltimore, Maryland.
JBJS Case Connector
|April 9, 2021
Summary
Selective androgen receptor modulators (SARMs) may increase the risk of Achilles tendon rupture in athletes. This case report highlights a powerlifter who experienced bilateral ruptures after SARM use.
Area of Science:
- Sports Medicine
- Orthopedic Surgery
- Pharmacology
Background:
- Anabolic androgenic steroids are known to negatively affect tendon health.
- Selective androgen receptor modulators (SARMs) are performance-enhancing drugs with potential anabolic effects.
- The impact of SARMs on musculoskeletal tissues, particularly tendons, requires further investigation.
Observation:
- A 36-year-old competitive powerlifter experienced simultaneous bilateral Achilles tendon ruptures.
- The ruptures occurred near the myotendinous junction.
- The athlete had recently used two different types of SARMs.
Findings:
- Surgical repair was performed for both Achilles tendon ruptures.
- Postoperative recovery involved immobilization, progressive weight-bearing, and rehabilitation.
- No complications were noted during the postoperative period.
Implications:
- This case suggests a potential link between SARM use and Achilles tendon rupture.
- Athletes and clinicians should be aware of the potential tendon risks associated with SARMs.
- Further research is warranted to elucidate the specific mechanisms by which SARMs may affect tendon integrity.

