Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Histology of the Gastrointestinal (GI) Tract01:20

Histology of the Gastrointestinal (GI) Tract

2.2K
The GI tract, from beginning to end, is made up of four continuous tissue layers that adjust their structure according to their specific roles. These layers, from innermost to outermost, are known as the mucosa, submucosa, muscularis, and serosa, which are continuous with the mesentery.
The mucosa is sometimes called a mucous membrane due to its mucus-secreting features. This membrane is composed of epithelium, which directly interacts with ingested substances, and the lamina propria, a layer...
2.2K
Gastrointestinal Motility Disorders01:20

Gastrointestinal Motility Disorders

760
Gastrointestinal or GI motility disorders are characterized by irregular gastrointestinal tract movements, disrupting food transit from the mouth to the anus. They are caused by damage or dysfunction in gut muscles or nerves. These disorders can cause symptoms such as severe constipation, diarrhea, abdominal pain, and swallowing difficulties. Disorders can affect any segment of the GI tract and range widely in severity, from common conditions like GERD to life-threatening conditions like...
760
Lymphoid Cells and Tissues01:18

Lymphoid Cells and Tissues

2.2K
Lymphoid cells and tissues are integral to the immune system, which is crucial in maintaining our body's defense against harmful pathogens. They form the building blocks of lymphoid organs, which include the spleen, thymus, and lymph nodes.
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
2.2K
Secondary Lymphoid Organs01:15

Secondary Lymphoid Organs

7.8K
Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
7.8K
Primary Lymphoid Organs01:16

Primary Lymphoid Organs

13.3K
Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
13.3K
Lymphatic Vessels and Lymph Transport01:16

Lymphatic Vessels and Lymph Transport

20.9K
Lymphatic vessels, known as lymphatics, are crucial in transporting lymph from peripheral tissues to our venous system. This process begins with lymph entering through tiny capillaries that branch through tissues. These capillaries have unique features such as larger diameters, thinner walls, and a distinctive one-way valve system formed by overlapping endothelial cells.
This one-way system allows fluids, solutes, and even pathogens to enter but prevents their return to the intercellular...
20.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Risk-based pathology reporting after endoscopic submucosal dissection for early gastrointestinal cancer: international consensus standards.

Gut·2026
Same author

Knowledge gaps in tubular gut tumours: a critical appraisal of the 6th edition of the World Health Organization classification of tumours.

The Journal of pathology·2026
Same author

Expanding the Spectrum of High-Risk Human Papilloma Virus (HPV)-Associated Glandular Neoplasms of the Anorectum.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc·2026
Same author

MRD testing in Hodgkin lymphoma: filling the knowledge gaps.

Blood·2026
Same author

Mantle cell lymphoma outcomes following sequential first-line bendamustine-rituximab and second-line Bruton's tyrosine kinase inhibitor therapy.

Blood cancer journal·2026
Same author

Genetically driven immune microenvironment states associate with therapeutic responses in MYD88 mutant lymphomas.

Molecular cancer·2026

Related Experiment Video

Updated: Nov 9, 2025

Long-Term Catheterization of the Intestinal Lymph Trunk and Collection of Lymph in Neonatal Pigs
06:25

Long-Term Catheterization of the Intestinal Lymph Trunk and Collection of Lymph in Neonatal Pigs

Published on: March 5, 2016

9.7K

Gastrointestinal Tract Lymphomas.

Jessica Alvarez-Lesmes1, Jennifer R Chapman1, Daniel Cassidy1

  • 1From the Department of Pathology, Division of Hematopathology, Division of Gastrointestinal Pathology, University of Miami Miller School of Medicine, Sylvester Comprehensive Cancer Center and Jackson Memorial Hospital, Miami, Florida (Alvarez-Lesmes, Chapman, Cassidy, Zhou, Garcia-Buitrago, Montgomery, Poveda).

Archives of Pathology & Laboratory Medicine
|April 9, 2021
PubMed
Summary

Gastrointestinal lymphoma is the most common extranodal lymphoma, predominantly B-cell lineage. Recognizing common GI lymphoma subtypes is crucial for effective patient management and treatment strategies.

More Related Videos

Isolation of Lamina Propria Mononuclear Cells from Murine Colon Using Collagenase E
09:48

Isolation of Lamina Propria Mononuclear Cells from Murine Colon Using Collagenase E

Published on: September 26, 2019

16.2K
Molecular and Immunologic Techniques in a Genetically Engineered Mouse Model of Gastrointestinal Stromal Tumor
07:21

Molecular and Immunologic Techniques in a Genetically Engineered Mouse Model of Gastrointestinal Stromal Tumor

Published on: May 2, 2022

2.3K

Related Experiment Videos

Last Updated: Nov 9, 2025

Long-Term Catheterization of the Intestinal Lymph Trunk and Collection of Lymph in Neonatal Pigs
06:25

Long-Term Catheterization of the Intestinal Lymph Trunk and Collection of Lymph in Neonatal Pigs

Published on: March 5, 2016

9.7K
Isolation of Lamina Propria Mononuclear Cells from Murine Colon Using Collagenase E
09:48

Isolation of Lamina Propria Mononuclear Cells from Murine Colon Using Collagenase E

Published on: September 26, 2019

16.2K
Molecular and Immunologic Techniques in a Genetically Engineered Mouse Model of Gastrointestinal Stromal Tumor
07:21

Molecular and Immunologic Techniques in a Genetically Engineered Mouse Model of Gastrointestinal Stromal Tumor

Published on: May 2, 2022

2.3K

Area of Science:

  • Gastroenterology
  • Hematology
  • Oncology

Background:

  • The gastrointestinal (GI) tract is the most frequent extranodal site for non-Hodgkin lymphoma, comprising 20-40% of all extranodal lymphomas.
  • While most GI lymphomas are secondary to systemic disease, primary GI lymphomas represent 10-15% of all non-Hodgkin lymphomas.
  • The predominant lineage involves B-cells, with diffuse large B-cell lymphoma being the most common subtype.

Purpose of the Study:

  • To review lymphoproliferative neoplasms of B-cell and T-cell lineage within the luminal GI tract.
  • To identify the most prevalent subtypes of GI lymphoma at each specific anatomic site.

Main Methods:

  • A systematic literature search of the PubMed database was conducted.
  • The search focused on updated information regarding GI lymphoma epidemiology, subtypes, clinical presentations, endoscopic findings, and genetic characteristics.
  • Histologic images were sourced from a collection of clinical cases.

Main Results:

  • The gastrointestinal tract is the most common extranodal site for lymphoproliferative neoplasms.
  • Diffuse large B-cell lymphoma is the most common subtype of non-Hodgkin lymphoma involving the GI tract.
  • Understanding prevalent GI lymphoma subtypes is essential for clinical practice.

Conclusions:

  • The GI tract serves as the primary site for extranodal lymphoproliferative neoplasms.
  • Accurate identification of common GI lymphomas is critical for optimal patient management and therapeutic decisions.