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Comprehensive Review of Cardiovascular Involvement in COVID-19
1Ruff Joseph Macale Cajanding is Charge Nurse, Adult Critical Care Unit, 6th Floor, King George V Building, St Bartholomew's Hospital, Barts Health NHS Trust, 2 King Edward Street, London EC1A 1HQ, United Kingdom (ruffcajanding@nhs.net).
Insights
This article details the cardiovascular effects of COVID-19, exploring its cardiac manifestations, pathophysiology, and management strategies for patients with heart conditions during the pandemic.
Area of Science:
- Infectious Diseases
- Cardiology
- Public Health
Background:
- COVID-19 (Coronavirus Disease 2019) is a global pandemic impacting multiple organ systems.
- While primarily respiratory, significant cardiovascular involvement is increasingly recognized.
- Healthcare systems face unprecedented demands due to the disease's severity.
Purpose of the Study:
- To present the current knowledge on cardiac involvement in COVID-19.
- To focus on cardiovascular manifestations and complications of COVID-19 infection.
- To explore mechanistic insights and pathophysiology of cardiac effects.
Main Methods:
- Review of current scientific literature and epidemiological reports.
- Analysis of clinical observations and case studies.
- Synthesis of evidence on COVID-19's impact on the cardiovascular system.
Main Results:
- COVID-19 infection leads to diverse cardiovascular manifestations.
- Pathophysiological mechanisms link viral infection to cardiac damage.
- Understanding these effects is crucial for patient outcomes.
Conclusions:
- Cardiac pathology is a significant concern in COVID-19 patients.
- Clinical management requires addressing cardiovascular complications.
- Further research is needed to refine treatment strategies for cardiac involvement.
Abstract:
COVID-19 has emerged as one of the most devastating and clinically significant infectious diseases of the last decade. It has reached global pandemic status at an unprecedented pace and has placed significant demands on health care systems worldwide. Although COVID-19 primarily affects the lungs, epidemiologic reports have shown that the disease affects other vital organs of the body, including the heart, vasculature, kidneys, brain, and the hematopoietic system. Of importance is the emerging awareness of the effects of COVID-19 on the cardiovascular system. The current state of knowledge regarding cardiac involvement in COVID-19 is presented in this article, with particular focus on the cardiovascular manifestations and complications of COVID-19 infection. The mechanistic insights of disease causation and the relevant pathophysiology involved in COVID-19 as they affect the heart are explored and described. Relevant practice essentials and clinical management implications for patients with COVID-19 with a cardiac pathology are presented in light of recent evidence.
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