Factors associated with hiatal hernia in neurologically impaired children

In Hyuk Yoo1, Jung Yeon Joo1, Hye Ran Yang1,2

  • 1Department of Pediatrics, Seoul National University Bundang Hospital, Seongnam, Korea.

Insights

Hiatal hernias in neurologically impaired children can lead to severe complications. Early predictors like prolonged neurological disease and aspiration pneumonia history aid in timely diagnosis and treatment.

Area of Science:

  • Pediatric Gastroenterology
  • Neurology

Background:

  • Hiatal hernia impairs the anti-reflux mechanism, increasing risk of gastroesophageal reflux-induced injury.
  • Diagnosis is critical in neurologically impaired children due to severe complications like aspiration pneumonia and malnutrition.
  • This study evaluated patient characteristics and early predictors of hiatal hernia in this population.

Purpose of the Study:

  • To identify early predictors of hiatal hernia in neurologically impaired children.
  • To facilitate timely diagnosis and management to prevent severe complications.

Main Methods:

  • Retrospective analysis of 97 neurologically impaired children.
  • Inclusion of esophagogastroduodenoscopy and upper gastrointestinal series findings.
  • Statistical analysis of demographic, clinical, endoscopic, and radiological data.

Main Results:

  • Hiatal hernia was diagnosed in 22.7% of patients.
  • Early predictors identified: neurological disease >6 months, wasting, enteral tube feeding, and history of aspiration pneumonia.
  • Significant odds ratios were calculated for each predictor.

Conclusions:

  • Early identification of hiatal hernia predictors is crucial for neurologically impaired children.
  • Prompt diagnosis enables optimal medical or surgical treatment.
  • Preventing complications like aspiration pneumonia and malnutrition is paramount.
Abstract

Related Concept Videos

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
76
Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
527
Disorders of the Nervous Tissue01:28

Disorders of the Nervous Tissue

Nervous tissue is a vital component of the human body's communication system, enabling us to perceive and respond to stimuli. However, like all other tissues, it is vulnerable to disorders and diseases that can significantly impact our neurological functioning.
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...
2.2K
Neurulation01:30

Neurulation

Neurulation is the embryological process which forms the precursors of the central nervous system and occurs after gastrulation has established the three primary cell layers of the embryo: ectoderm, mesoderm, and endoderm. In humans, the majority of this system is formed via primary neurulation, in which the central portion of the ectoderm—originally appearing as a flat sheet of cells—folds upwards and inwards, sealing off to form a hollow neural tube. As development proceeds, the...
43.7K
Esophageal Strictures-I: Introduction01:30

Esophageal Strictures-I: Introduction

Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
357
Bulimia Nervosa01:30

Bulimia Nervosa

Bulimia nervosa is a complex and severe eating disorder characterized by a cyclical pattern of binge-and-purge eating pattern. It generally involves an episode of binge eating, followed by compensatory behaviors such as vomiting, excessive exercise, laxative use, or fasting, to prevent weight gain. Despite often maintaining a normal weight, individuals with bulimia are intensely preoccupied with their body image and harbor an overwhelming fear of gaining weight. This can contribute to the...
307