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Updated: Nov 9, 2025

Fabrication of a Dipole-assisted Solid Phase Extraction Microchip for Trace Metal Analysis in Water Samples
Published on: August 7, 2016
Recent advances and applications of cyclodextrins in magnetic solid phase extraction
Mahshid Majd1, Mina Yazdanpanah1, Mohammad Reza Bayatloo1
1Department of Analytical Chemistry and Pollutants, Shahid Beheshti University, G. C., P.O. Box 519396-4716, Evin, Tehran, Iran.
Cyclodextrins (CDs) are versatile cyclic oligosaccharides used in magnetic solid-phase extraction (MSPE). This review details CD-based magnetic sorbents for efficient analyte extraction from various samples.
Area of Science:
- Analytical Chemistry
- Materials Science
- Separation Science
Background:
- Cyclodextrins (CDs) are cyclic oligosaccharides with unique host-guest complexation abilities.
- CDs are utilized in chromatography (HPLC, GC) and capillary electrophoresis (CE) as chiral selectors.
- Recent applications involve modifying sorbents for solid-phase extraction (SPE).
Purpose of the Study:
- To review the synthesis of cyclodextrin-based magnetic sorbents.
- To explore the application of these sorbents in magnetic solid-phase extraction (MSPE).
- To discuss the potential of CD-based sorbents for sample pre-treatment.
Main Methods:
- Synthesis of CD-based magnetic sorbents via immobilization, nanosponges, and hybrid materials.
- Application of these sorbents in magnetic solid-phase extraction (MSPE).
- Analysis of analytes from biological, environmental, and food samples.
Main Results:
- CD-based magnetic sorbents offer efficient analyte extraction.
- MSPE provides rapid phase separation compared to traditional SPE.
- These sorbents are effective for diverse sample matrices.
Conclusions:
- CD-based magnetic sorbents represent a promising tool for sample preparation.
- Further development can enhance their utility in analytical chemistry.
- The review highlights the growing importance of CD-based materials in separation science.
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