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Ultrasound Assessment of Endothelial-Dependent Flow-Mediated Vasodilation of the Brachial Artery in Clinical Research
Published on: October 22, 2014
Haemorrhoidal haemodynamic changes in patients with haemorrhoids treated using Doppler-guided dearterialization
A Parello1, F Litta1, V De Simone1
1Proctology Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCSS, Rome, Italy.
Transanal hemorrhoidal dearterialization (THD) significantly alters blood flow in hemorrhoidal piles, reducing arterial hyperflow. This surgical intervention leads to improved patient symptoms and hemodynamic parameters.
Area of Science:
- Vascular Surgery
- Gastroenterology
- Medical Imaging
Background:
- Arterial hyperflow is a potential contributing factor in hemorrhoidal disease.
- Transanal hemorrhoidal dearterialization (THD) is a surgical technique used for hemorrhoid treatment.
Purpose of the Study:
- To evaluate the impact of THD on hemodynamic parameters within hemorrhoidal tissues.
- To assess changes in blood flow characteristics after THD surgery.
Main Methods:
- Endoanal ultrasonography and color Doppler imaging were used to assess internal hemorrhoids.
- Hemodynamic parameters including peak systolic velocity, pulsatility index, and resistivity index were measured before and 1 year after THD.
- Symptom severity was quantified using a standardized questionnaire.
Main Results:
- Postoperative measurements showed a significant decrease in peak systolic velocity, pulsatility index, and resistivity index.
- Acceleration time significantly increased, while end-diastolic velocity remained unchanged.
- All patients experienced significant symptom improvement or resolution within one year, with a marked reduction in symptom severity scores.
Conclusions:
- THD effectively modifies key hemodynamic parameters in internal hemorrhoids.
- The procedure is associated with a reduction in arterial hyperflow, correlating with clinical improvement.
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