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Systemic manifestations of COVID-19
Rubina K Mahajan1, Gunchan Paul1, Ramit Mahajan2
1Department of Critical Care Medicine, Dayanand Medical College and Hospital, Ludhiana, Punjab, India.
Journal of Anaesthesiology, Clinical Pharmacology
|April 12, 2021
Summary
Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, affects multiple organ systems beyond the respiratory tract. Healthcare professionals must maintain high suspicion for atypical COVID-19 presentations across all patient groups.
Area of Science:
- Infectious Diseases
- Public Health
- Internal Medicine
Background:
- Coronavirus disease 2019 (COVID-19), caused by the novel SARS-CoV-2, is a global health emergency.
- While primarily a respiratory illness, COVID-19 exhibits diverse clinical manifestations.
- Reports indicate involvement of multiple organ systems globally.
Purpose of the Study:
- To review the systemic effects of COVID-19.
- To highlight the varied presentations of SARS-CoV-2 infection.
- To emphasize the need for clinical vigilance among healthcare workers.
Main Methods:
- Systematic review of reported COVID-19 cases.
- Consolidation of findings on organ system involvement.
- Analysis of atypical disease manifestations.
Main Results:
- COVID-19 affects not only the respiratory system but also cardiovascular, gastrointestinal, renal, hepatic, endocrine, and nervous systems.
- Atypical presentations are increasingly recognized worldwide.
- The spectrum of SARS-CoV-2 impact is broad and multifaceted.
Conclusions:
- COVID-19 presents with a wide range of systemic effects.
- Healthcare providers require heightened awareness and a high index of suspicion for diagnosing COVID-19.
- Early recognition of diverse symptoms is crucial for patient management.
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