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Continuous-flow left ventricular assist device systems infections: current outcomes and management strategies

Nana Aburjania1, Christine M Hay2, Muhammad R Sohail3

  • 1Division of Infectious Diseases, Department of Medicine, Thomas Jefferson University, Philadelphia, PA, USA.

Annals of Cardiothoracic Surgery
|April 12, 2021
PubMed

Insights

Diagnosing and treating infections associated with left ventricular assist devices (LVADs) is complex. This review discusses current diagnostic tools and treatment strategies for LVAD infections in advanced heart failure patients.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Biomedical Engineering

Background:

  • Left ventricular assist devices (LVADs) are crucial for managing advanced heart failure.
  • Infections are a frequent and challenging complication in LVAD patients.
  • Current management strategies for LVAD infections lack standardized clinical trials.

Purpose of the Study:

  • To review recent diagnostic modalities for LVAD infections.
  • To discuss current treatment approaches for LVAD infections.
  • To provide guidance on the diagnosis and management of LVAD infections.

Main Methods:

  • Literature review of diagnostic techniques.
  • Analysis of treatment strategies for LVAD-related infections.
  • Synthesis of expert recommendations for clinical practice.

Main Results:

  • Multiple diagnostic tools exist for LVAD infections, but their efficacy varies.
  • Treatment is complicated by the presence of the implanted device.
  • No definitive clinical trials guide optimal diagnosis or treatment.

Conclusions:

  • Accurate diagnosis and effective treatment of LVAD infections remain challenging.
  • A multidisciplinary approach is essential for managing these complex cases.
  • Further research and clinical trials are needed to establish best practices.
Keywords:
Left ventricular assisted device (LVAD)infectionmanagementoutcomes

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