Mycosis Fungoides: Uncommon Presentation.

Area of Science:

• Dermatology
• Oncology
• Pathology

Background:

• Mycosis fungoides is the most common type of cutaneous T cell lymphoma.
• Advanced stages, including tumor and ulcerative forms, present significant diagnostic and therapeutic challenges.
• Misdiagnosis can delay appropriate treatment for this rare malignancy.

Observation:

• A patient presented with widespread ulcerated plaques and nodules.
• Lesions were initially misdiagnosed and treated as leprosy without improvement.
• The infraorbital region was notably affected, complicating the clinical picture.

Findings:

• The clinical presentation mimicked other dermatological conditions, including leprosy.
• Histopathological examination of skin lesions was essential for definitive diagnosis.
• The case underscores the importance of considering lymphoma in persistent, unresponsive dermatoses.

Implications:

• Misdiagnosis can lead to delayed treatment and disease progression.
• Integrated clinical and histopathological assessment improves diagnostic accuracy for mycosis fungoides.
• Raising awareness of atypical presentations can aid clinicians in identifying cutaneous T cell lymphoma earlier.