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Post-percutaneous coronary intervention angina: From physiopathological mechanisms to individualized treatment

Leonardo De Luca1, Giuseppe M C Rosano2, Ilaria Spoletini2

  • 1Department of Cardiosciences, A.O. San Camillo Forlanini, Roma, Italy. leo.deluca@libero.it.

Cardiology Journal
|April 12, 2021
PubMed

Insights

Chronic ischemic heart disease (IHD) can persist after percutaneous coronary intervention (PCI). This review explores the causes, diagnosis, and management of ongoing angina following PCI, aiming to improve patient outcomes.

Area of Science:

  • Cardiology
  • Vascular Medicine
  • Medical Research

Background:

  • Chronic ischemic heart disease (IHD) is a complex condition with diverse causes.
  • Percutaneous coronary intervention (PCI) is a common treatment to reduce angina in IHD patients.
  • Persistent anginal symptoms post-PCI negatively impact quality of life and prognosis.

Purpose of the Study:

  • To review the pathogenic mechanisms of angina after PCI.
  • To outline the diagnostic challenges of post-PCI angina.
  • To discuss management strategies for patients experiencing angina post-PCI.

Main Methods:

  • Literature review of pathogenic mechanisms.
  • Analysis of diagnostic approaches for persistent angina.
  • Synthesis of current management guidelines and therapeutic options.

Main Results:

  • Identified multifactorial etiologies for post-PCI angina.
  • Highlighted difficulties in diagnosing the precise cause of residual symptoms.
  • Summarized therapeutic interventions and their limitations.

Conclusions:

  • Post-PCI angina remains a significant clinical challenge.
  • Understanding underlying mechanisms is crucial for effective diagnosis and management.
  • Further research is needed to optimize treatment strategies for improved patient outcomes.

Keywords:
anginaischemic heart diseasemedical therapypercutaneous coronary interventionquality of life

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