Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Genetic Screens02:46

Genetic Screens

5.3K
Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which...
5.3K
Behavioral Genetics and Its Designs01:23

Behavioral Genetics and Its Designs

732
Behavior genetics explores how genetic inheritance influences human behavior. It focuses on how genes, passed from parents to offspring, contribute to the development of behavioral traits and tendencies. This branch of genetics seeks to understand the complex interplay between inherited genetic factors and environmental influences in shaping our behaviors.
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
732
Bioequivalence Experimental Study Designs: Repeated Measures, Cross-Over, Carry-Over, and Latin Square Designs01:15

Bioequivalence Experimental Study Designs: Repeated Measures, Cross-Over, Carry-Over, and Latin Square Designs

58
Body:Bioequivalence experimental study designs play a pivotal role in testing the effectiveness of various treatments. Key among these are the repeated measures, cross-over, carry-over, and Latin square designs. In the repeated measures design, each subject receives all treatments, allowing for temporal comparisons. This type of design is useful in reducing variability but requires careful planning to avoid bias.The cross-over design, an economical method, involves sequential administration of...
58
Experimental Designs01:16

Experimental Designs

16.2K
An experimental design is a systematic process that allows researchers to evaluate the relationship between dependent and independent variables. There are three widely used types of experimental design - pre-experimental design, true experimental design, and quasi-experimental design. In pre-experimental design, the researcher compares the data before and after some interventions or treatments. The true-experimental design has more than one purposefully created group, a commonly measured...
16.2K
Hardy-Weinberg Principle01:49

Hardy-Weinberg Principle

75.0K
Diploid organisms have two alleles of each gene, one from each parent, in their somatic cells. Therefore, each individual contributes two alleles to the gene pool of the population. The gene pool of a population is the sum of every allele of all genes within that population and has some degree of variation. Genetic variation is typically expressed as a relative frequency, which is the percentage of the total population that has a given allele, genotype or phenotype.
75.0K
Study Design in Statistics01:15

Study Design in Statistics

9.7K
A study design is a set of techniques that allow a researcher to collect and analyze data from different variables defined for a specific research problem. Statistics is commonly for effective study design and more robust experiments,
Does aspirin reduce the risk of heart attacks? Is one brand of fertilizer more effective at growing roses than another? Is fatigue as dangerous to a driver as the influence of alcohol? Questions like these are answered using randomized experiments with proper...
9.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Regulation of Small RNAs by Exercise and Their Role in Insulin Sensitivity.

bioRxiv : the preprint server for biology·2026
Same author

Varying Influence of Menstrual Cycle Phase and Hormonal Contraceptive Use on Resistance Exercise-Induced Circulating Extracellular Vesicle and Metabolite Signalling.

Journal of extracellular vesicles·2026
Same author

Sex-specific skeletal muscle gene expression responses to exercise reveal novel direct mediators of insulin sensitivity change.

NAR molecular medicine·2025
Same author

Muscle Strength and Size Relationships with Unilateral Progressive Resistance Training.

bioRxiv : the preprint server for biology·2025
Same author

Genome-Wide Genetic Analysis of Dropout in a Controlled Exercise Intervention in Sedentary Adults With Overweight or Obesity and Cardiometabolic Disease.

Annals of behavioral medicine : a publication of the Society of Behavioral Medicine·2024
Same author

Acute Resistance Exercise Modifies Extracellular Vesicle miRNAs Targeting Anabolic Gene Pathways: A Prospective Cohort Study.

Medicine and science in sports and exercise·2024
Same journal

Cardiorespiratory Fitness and Age-Related Decline in Kidney Function among Individuals with Preserved Kidney Health: The Aging Kidney Study.

Medicine and science in sports and exercise·2026
Same journal

Objectively Measured Cardiorespiratory Fitness as a Potential Biomarker for Alzheimer's Disease Risk in Older Adults: Evidence from the Generation 100 Study.

Medicine and science in sports and exercise·2026
Same journal

The Effects of Eight-Week Traditional Aerobic Exercise and Exergaming on Dual-Task Performance and Prefrontal Cortex Activation in Older Adults.

Medicine and science in sports and exercise·2026
Same journal

The Impact of Cardiorespiratory Fitness on Cytotoxic T Cell Metabolism and Function.

Medicine and science in sports and exercise·2026
Same journal

Female Athletes Through the Lifespan: Clinical Considerations and a Call for Comprehensive Sports Medicine Healthcare.

Medicine and science in sports and exercise·2026
Same journal

Artificial Intelligence in Exercise Science and Sports Medicine.

Medicine and science in sports and exercise·2026
See all related articles

Related Experiment Video

Updated: Nov 9, 2025

Efficient Sampling of Genetically Encoded Biosensor Design Space Enabled with a Design of Experiments and Automation Workflow
08:58

Efficient Sampling of Genetically Encoded Biosensor Design Space Enabled with a Design of Experiments and Automation Workflow

Published on: October 17, 2025

165

Systems Exercise Genetics Research Design Standards.

J Timothy Lightfoot1, Stephen M Roth2, Monica J Hubal3

  • 1Department of Health and Kinesiology and the Sydney and JL Huffines Institute for Sports Medicine and Human Performance, Texas A&M University, College Station, TX.

Medicine and Science in Sports and Exercise
|April 12, 2021
PubMed
Summary
This summary is machine-generated.

Genetic and genomic factors significantly influence exercise traits. This commentary offers best-practice recommendations for researchers in exercise genetics to improve study quality and publication standards.

More Related Videos

Characterization of Complex Systems Using the Design of Experiments Approach: Transient Protein Expression in Tobacco as a Case Study
20:24

Characterization of Complex Systems Using the Design of Experiments Approach: Transient Protein Expression in Tobacco as a Case Study

Published on: January 31, 2014

16.8K
Measuring Exercise Levels in Drosophila melanogaster Using the Rotating Exercise Quantification System REQS
04:53

Measuring Exercise Levels in Drosophila melanogaster Using the Rotating Exercise Quantification System REQS

Published on: May 27, 2018

7.7K

Related Experiment Videos

Last Updated: Nov 9, 2025

Efficient Sampling of Genetically Encoded Biosensor Design Space Enabled with a Design of Experiments and Automation Workflow
08:58

Efficient Sampling of Genetically Encoded Biosensor Design Space Enabled with a Design of Experiments and Automation Workflow

Published on: October 17, 2025

165
Characterization of Complex Systems Using the Design of Experiments Approach: Transient Protein Expression in Tobacco as a Case Study
20:24

Characterization of Complex Systems Using the Design of Experiments Approach: Transient Protein Expression in Tobacco as a Case Study

Published on: January 31, 2014

16.8K
Measuring Exercise Levels in Drosophila melanogaster Using the Rotating Exercise Quantification System REQS
04:53

Measuring Exercise Levels in Drosophila melanogaster Using the Rotating Exercise Quantification System REQS

Published on: May 27, 2018

7.7K

Area of Science:

  • Exercise genetics and genomics
  • Molecular biology and exercise science

Background:

  • Genetic and genomic factors significantly impact diverse sport and exercise characteristics, including endurance, strength, and physical activity.
  • The field of exercise systems genetics has grown substantially, but many researchers lack extensive molecular biology or genomics training.
  • This knowledge gap can lead to flawed research and hinder publication in high-impact journals.

Purpose of the Study:

  • To provide researchers, particularly those without a genetics background, with best-practice recommendations for research standards and data analysis in exercise systems genetics.
  • To address observed flaws in submitted manuscripts, often stemming from a lack of familiarity with current methodologies and literature.
  • To enhance the quality and rigor of scientific literature in the evolving field of exercise genetics.

Main Methods:

  • Review of scientific literature on genetic and genomic factors in exercise.
  • Analysis of common flaws in submitted manuscripts in exercise genetics.
  • Development of recommendations based on "state-of-the-art" methods and established literature.

Main Results:

  • Identified significant roles of genetic and genomic factors in exercise traits.
  • Observed common methodological and analytical flaws in exercise genetics research.
  • Highlighted the need for improved training and adherence to best practices.

Conclusions:

  • Adherence to best-practice research standards and data analysis is crucial for advancing the field of exercise systems genetics.
  • Providing clear guidelines will strengthen the quality of research and publications.
  • This commentary aims to foster higher-quality, cutting-edge research in exercise genetics.