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Arterial vascular access complication in osteogenesis imperfecta.

Asim Chughtai1, Ramita Dey2, Sudipta Chattopadhyay1,3

  • 1Department of Cardiology, Bedford Hospital, Bedford, UK.

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|April 13, 2021
PubMed
Summary

Catastrophic femoral bleeding occurred in a patient with Osteogenesis Imperfecta (OI) during a coronary angiogram. This rare complication required a covered stent for treatment, highlighting a potential risk in OI patients.

Keywords:
Osteogenesis imperfectaangioplastycollagen vascular diseasecoronary angiogramfemoral arterypercutaneous coronary intervention

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Area of Science:

  • Cardiology
  • Vascular Surgery
  • Genetics

Background:

  • Coronary angiograms are common procedures.
  • Osteogenesis Imperfecta (OI) is a rare genetic disorder affecting bone fragility.
  • Femoral artery access is a standard approach for cardiac catheterization.

Observation:

  • A patient with Type 1 Osteogenesis Imperfecta (OI) experienced severe bleeding from the femoral artery access site.
  • The bleeding occurred after an otherwise uncomplicated femoral puncture during a coronary angiogram.
  • This complication is exceptionally rare in patients with OI.

Findings:

  • The catastrophic bleeding necessitated immediate intervention.
  • A covered stent was deployed at the femoral puncture site to control the hemorrhage.
  • The case highlights a potentially serious, albeit rare, vascular complication in OI patients.

Implications:

  • Interventionists should be aware of this rare but severe complication in OI patients undergoing femoral procedures.
  • Understanding the pathological mechanisms may improve risk assessment and management strategies.
  • This case underscores the importance of vigilance for vascular complications in patients with connective tissue disorders.