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Updated: Nov 9, 2025

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
Published on: August 8, 2025
Arterial vascular access complication in osteogenesis imperfecta
Asim Chughtai1, Ramita Dey2, Sudipta Chattopadhyay1,3
1Department of Cardiology, Bedford Hospital, Bedford, UK.
Abstract:
We present a case of the catastrophic bleeding from the femoral access site after an uncomplicated puncture in a patient with Type 1 osteogenesis imperfecta (OI) undergoing coronary angiogram via the femoral route. This had to be treated with a covered stent at the puncture site. This is an extremely rare complication in OI. The potential pathological mechanisms of this complication are discussed. An interventionist will rarely encounter such a patient in the catheterisation laboratory but would do well to be aware of this potential complication.
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