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Structure, Function and Modulation of Striatal-enriched Protein Tyrosine Phosphatase (STEP)

Xiao Liang1, Xuben Hou1, Hao Fang1

  • 1Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Science, Cheeloo College of Medicine, Shandong University, Ji'nan, Shandong 250012, China.

Current Medicinal Chemistry
|April 13, 2021
PubMed
Summary

Striatal-enriched protein tyrosine phosphatase (STEP) is a key regulator in the central nervous system. Inhibiting STEP shows promise for treating neurological disorders like Alzheimer's disease.

Keywords:
PTP domain.Striatal-enriched protein tyrosine phosphataseactivatorinhibitornervous system diseasesstructureactivity relationships

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