Related Experiment Video
Updated: Nov 9, 2025

Quantitation of Intra-peritoneal Ovarian Cancer Metastasis
Published on: July 18, 2016
Disseminated ovarian granulosa cell tumor after laparoscopic surgery: Two case reports
Man-Hua Cui1, Xi-Wen Zhang, Li-Ping Zhao
1Department of Gynecology and Obstetrics, The Second Hospital of Jilin University, Changchun, Jilin Province, China.
Rationale:
Granulosa cell tumors (GCT) have an incidence of 0.6 to 0.8/100,000. Short-term relapsed ovarian GCT is extremely rare. Herein, this report aims to present 2 rare cases of disseminated ovarian GCT and analyze the causes of recurrence.
Patient Concerns:
The 2 patients presented with abdominal pain.
Diagnosis:
Both the patients were diagnosed with relapsed ovarian GCT (IIIc stage) in the adult type.
Interventions:
The 2 patients had a medical history of surgery for ovarian GCT by using laparoscopic with power morcellators (LPM). They experienced relapsed ovarian GCT postoperatively. Subsequently, they received a repeated operation through a laparotomy approach. Numerous malignant metastasis neoplasms were detected at the port-sites. Then, tumor resection was performed.
Outcomes:
The postoperative pathologies of both case 1 and case 2 reported ovarian GCT (IIIc stage) in adult type. The 2 patients presented disease-free survival for more than 33 months follow-up period.
Lessons:
The application of LPM may be a risk factor of disseminated ovarian GCT. However, laparoscopic surgery is still an optimal treatment strategy for ovarian tumors. Besides, gynecologists should comply with the tumor-free principle during surgery.

