Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Extraction of sulfamethazine from feed samples.

W J Blanchflower¹, D A Rice

¹Department of Agriculture, Veterinary Research Laboratories, Stormont, Belfast, Northern Ireland.

Journal - Association of Official Analytical Chemists

|March 1, 1988

Summary

Evaluating extraction solvents for sulfamethazine in animal feed revealed inconsistent recoveries. A 75% methanol acetic acid solution demonstrated the best performance for extracting this veterinary antibiotic from pelleted feed samples.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Factors associated with persistent opioid use 6-12 months after primary total knee arthroplasty.

Anaesthesia·2022

Same author

The effect of intra-operative hypotension on acute kidney injury, postoperative mortality and length of stay following emergency hip fracture surgery.

Anaesthesia·2021

Same author

Steroids to reduce the impact on delirium (STRIDE): a double-blind, randomised, placebo-controlled feasibility trial of pre-operative dexamethasone in people with hip fracture.

Anaesthesia·2021

Same author

Persistent postoperative pain after total knee arthroplasty: a prospective cohort study of potential risk factors.

British journal of anaesthesia·2018

Same author

Transcranial direct current stimulation for upper limb neuropathic pain: A double-blind randomized controlled trial.

European journal of pain (London, England)·2018

Same author

TENS Alleviates Muscle Weakness Attributable to Attenuation of Ia Afferents.

International journal of sports medicine·2017

Area of Science:

Analytical Chemistry
Food Science
Veterinary Pharmacology

Background:

Sulfamethazine is a widely used sulfonamide antibiotic in animal husbandry.
Accurate quantification of sulfamethazine in feed is crucial for ensuring animal health and food safety.
Existing extraction methods show variable efficiency for sulfamethazine detection in feed matrices.

Purpose of the Study:

To evaluate the efficiency of various published extraction solvents for sulfamethazine in feed.
To identify optimal extraction conditions for reliable sulfamethazine analysis in pelleted feed.

Main Methods:

Comparative evaluation of multiple extraction solvents.
Extraction of sulfamethazine from commercially pelleted feed samples.
Quantification of extraction recovery percentages.

Main Results:

Several tested solvents yielded poor recoveries of sulfamethazine from pelleted feed.
Recoveries ranged widely from 48% to 94% with different solvents.
A 75% methanol acetic acid extractant provided the highest and most consistent recovery rates.

Conclusions:

The choice of extraction solvent significantly impacts sulfamethazine recovery in feed analysis.
A 75% methanol acetic acid solution is recommended as an effective extractant for sulfamethazine in pelleted feed.
Optimized extraction methods are essential for accurate monitoring of veterinary drug residues.

Related Experiment Videos