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Updated: Nov 9, 2025

A Data-Driven Approach to Quantifying Immune States in Sepsis
Published on: February 7, 2025
Prognostic tools for elderly patients with sepsis: in search of new predictive models
Fernando-Miguel Gamboa-Antiñolo1
1Internal Medicine, Hospital Universitario de Valme, Universidad de Sevilla, Ctra Cadiz S/N, 41700, Sevilla, Spain. minfga@us.es.
Abstract:
As a tool to support clinical decision-making, Mortality Prediction Models (MPM) can help clinicians stratify and predict patient risk. There are numerous scoring systems for patients with sepsis that predict sepsis-related mortality and the severity of sepsis. But there are currently no MPMs for adults with sepsis who meet the criteria of "good." Clinicians are unlikely to use complex MPMs that require extensive or expensive data collection to impede workflow. Machine learning applied to minimal medical records of patients diagnosed with sepsis can be a useful tool. Progress is needed in the development and validation of clinical decision support tools that can assist in patient risk stratification, prognosis, discussion of patient outcomes, and shared decision making.
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