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Upper Extremity Deep Vein Thrombosis After Botulinum Toxin Injection: A Case Report
Nana Lim1, Geun Su Lee1, Ki Hong Won1
1Department of Rehabilitation Medicine, Kwangju Christian Hospital, Gwangju, Korea.
Annals of Rehabilitation Medicine
|April 14, 2021
Summary
Deep vein thrombosis (DVT) can occur after botulinum toxin (BoNT) injections, even in the upper limb. Prompt anticoagulation therapy effectively resolved the DVT in this case.
Area of Science:
- Neurology
- Vascular Medicine
- Medical Case Reports
Background:
- Botulinum toxin (BoNT) injections are a common treatment for spasticity.
- Potential side effects include local pain, inflammation, swelling, and redness at the injection site.
Observation:
- A 37-year-old male presented with spasticity and dystonia in his left upper extremity.
- Following BoNT-A injection into the biceps brachii and brachialis, the patient developed symptoms suggestive of DVT.
Findings:
- Deep vein thrombosis (DVT) was diagnosed in the left cephalic vein via CT venography.
- The DVT resolved completely after anticoagulation therapy with rivaroxaban.
Implications:
- This case highlights a rare but serious complication of BoNT injections.
- Potential mechanisms include strenuous activity, muscle stasis, and direct vessel injury.
- Awareness and prompt management are crucial for patients experiencing DVT symptoms post-BoNT treatment.
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