Nebulized Saline Solution: A Multidimensional Voice Analysis

Area of Science:

• Laryngology and Voice Science
• Respiratory Therapy
• Acoustic Analysis of Voice

Background:

• Dysphonia, or voice disorder, affects vocal fold function and self-perception.
• Nebulization is a common method for delivering respiratory treatments.
• The impact of nebulization on voice parameters in both healthy and disordered voices requires comprehensive investigation.

Purpose of the Study:

• To assess the effects of nebulization on acoustic, perceptual-auditory, aerodynamic, and electroglottographic parameters.
• To evaluate changes in laryngeal function and self-perceived vocal discomfort post-nebulization.
• To compare the effects of nebulization in individuals with and without dysphonia.

Main Methods:

• Vocal, laryngeal, and self-perception evaluations were conducted before and after a 10-minute nebulization period.
• Acoustic, aerodynamic, and electroglottography (EGG) measurements were analyzed.
• Statistical analysis included Paired T-Student and Wilcoxon tests for parametric and non-parametric data, respectively, and Pearson's Chi-square for categorical variables.

Main Results:

• Nebulization positively impacted vocal and laryngeal parameters, particularly in non-dysphonic individuals.
• Electroglottography (EGG) revealed increased Closed Quotient (CQ) in all groups, indicating enhanced vocal fold closure.
• Improvements were observed in aerodynamic efficiency and self-perceived vocal discomfort across all groups, with enhanced mucosal wave in non-dysphonic individuals.

Conclusions:

• Nebulization with saline solution enhances acoustic measurements, EGG closed quotient, and vocal self-perception in both dysphonic and non-dysphonic individuals.
• The procedure improves vocal fold mucosal wave function in non-dysphonic individuals and aerodynamic efficiency in men.
• Nebulization offers a beneficial hydration strategy for voice improvement.