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Updated: Nov 9, 2025

A Mouse Model for Pathogen-induced Chronic Inflammation at Local and Systemic Sites
Published on: August 8, 2014
Aortic valve endocarditis by Actinomyces odontolyticus and Gemella morbillorum oral pathogens
Kishan Patel1, Matt MacDonald1, Hosam Hmoud1
1Zucker School of Medicine at Hofstra Northwell, Department of Internal Medicine, Lenox Hill Hospital New York, New York, United States.
Abstract:
A 56-year-old female with a history of poor dental hygiene and aortic insufficiency status post aortic valve replacement in 2015 presented with chest pain and fevers. She was found to have portal vein thrombosis, colitis, and infective endocarditis with aortic valve thickening. Blood cultures were positive for Actinomyces odontolyticus and Gemella morbillorum. Transesophageal echocardiogram was positive for aortic root thickening. Patient was treated with ceftriaxone and apixaban with full recovery.
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