Neurons in the basal forebrain complex of the rat: a Golgi study

Several types of neurons are coexistent in the basal forebrain nuclear complex of the rat. In the medial septum and vertical limb of the diagonal band 3 classes of neurons occur which are characterized by varicose dendrites. In the horizontal limb of the diagonal band neurons with smooth dendrites and those with varicose dendrites are intermingled. We found 3 classes of neurons in the nucleus preopticus magnocellularis. A giant type with smooth and varicose dendrites occurs in this nucleus, but also in the substantia innominata. In the substantia innominata-nucleus basalis complex 4 classes of neurons with varicose dendrites and 2 classes with spiny dendrites have been observed. Our findings suggest that the nucleus of the vertical limb of the diagonal band forms a unit with the nucleus septi medialis, but is separated from the nucleus of the horizontal limb of the diagonal band by different neuronal composition. The nucleus preopticus magnocellularis is a separate nuclear structure characterized by a content of neurons different from those in the horizontal limb of the diagonal band and in most components also from the substantia innominata-nucleus basalis complex. There is some evidence that the cholinergic neurons have to be searched among those with varicose dendrites.