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Updated: Nov 9, 2025
Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression
Published on: June 15, 2019
Updates and controversies in the early management of sepsis and septic shock
Ashley B. Norse1, Faheem Guirgis2, Lauren Page Black3
1Associate Professor & Associate Chair, Clinical Operations; Medical Director, Emergency Medicine Clinical Center University of Florida – Jacksonville, Jacksonville, FL
Abstract:
Sepsis is a common and life-threatening condition that requires early recognition and swift initial management. Diagnosis and treatment of sepsis and septic shock are fundamental for emergency clinicians, and include knowledge of clinical and laboratory indicators of subtle and overt organ dysfunction, infection source control, and protocols for prompt identification of the early signs of septic shock. This issue is a structured review of the literature on the management of sepsis, focusing on the current evidence, guidelines, and protocols.
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