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Updated: Nov 9, 2025

Microfluidic Fabrication of Polymeric and Biohybrid Fibers with Predesigned Size and Shape
Published on: January 8, 2014
New Silk Road: From Mesoscopic Reconstruction/Functionalization to Flexible Meso-Electronics/Photonics Based on
Chenyang Shi1, Fan Hu1, Ronghui Wu1
1College of Ocean and Earth Sciences, College of Materials, College of Physical Science and Technology, State Key Laboratory of Marine Environmental Science (MEL), Research Institute for Biomimetics and Soft Matter, Xiamen University, 422 Siming Nan Road, Xiamen, 361005, P. R. China.
Researchers transformed silk fibroin (SF) into advanced materials for functional electronic and optical devices. This mesoscopic functionalization strategy enables novel bio-compatible, flexible devices for sensing and electronics.
Area of Science:
- Materials Science
- Biomaterials Engineering
- Nanotechnology
Background:
- Silk fibroin (SF) is a natural protein with potential for advanced material applications.
- Developing functional electronic and optical materials from SF remains a key challenge.
- Mesoscopic reconstruction offers a novel approach to tailor SF properties.
Purpose of the Study:
- To review strategies for mesoscopic functionalization of silk fibroin (SF).
- To explore the fabrication of meso flexible SF-based electronic and optical devices.
- To highlight the potential applications of these advanced SF materials.
Main Methods:
- Mesoscopic reconstruction of hierarchical SF structures.
- Meso-nucleation templating to reroute SF molecule refolding.
- Fabrication of functionalized SF materials for device applications.
Main Results:
- Novel SF materials with enhanced properties were achieved through mesoscopic reconstruction.
- Functionalized SF materials were successfully fabricated into various meso flexible devices.
- Developed SF materials exhibit potential for nonlinear photonic, fluorescent, and electronic applications.
Conclusions:
- Mesoscopic functionalization is a viable strategy for creating advanced SF materials.
- SF-based devices offer biocompatibility, biodegradability, and flexibility for diverse applications.
- These functionalized SF materials pave the way for high-performance silk meso-electronics and bio-integrated systems.

