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Research Progress in Targeted Therapy of Hepatocellular Carcinoma
1Department of Gastroenterology, the Affiliated Nanhua Hospital, University of South China, Hengyang, Hunan Province 421002, China.
Abstract:
Hepatocellular carcinoma (HCC) is one of the most common malignancies, and its treatment is limited. With the understanding of key genes and signaling pathways in the occurrence and development of HCC, targeted drugs with high selectivity and low toxicity have been developed continuously, bringing a variety of options for the treatment of advanced HCC. In this article, the research progress on representative drugs of targeted therapy and potential therapeutic targets for HCC are reviewed.
Insights
Targeted therapies offer new options for advanced hepatocellular carcinoma (HCC) treatment. This review covers progress in targeted drugs and potential therapeutic targets for HCC, improving patient outcomes.
Area of Science:
- Oncology
- Molecular Biology
- Pharmacology
Background:
- Hepatocellular carcinoma (HCC) is a prevalent malignancy with limited treatment options.
- Advances in understanding HCC's molecular mechanisms have paved the way for targeted therapies.
Purpose of the Study:
- To review research progress on targeted therapy drugs for HCC.
- To identify and discuss potential therapeutic targets for HCC treatment.
Main Methods:
- Literature review of recent studies on HCC targeted therapy.
- Analysis of key genes and signaling pathways involved in HCC development.
Main Results:
- Development of targeted drugs with improved selectivity and reduced toxicity.
- Identification of several promising therapeutic targets for advanced HCC.
Conclusions:
- Targeted therapy has significantly expanded treatment options for advanced HCC.
- Continued research into novel targets and drugs is crucial for further improving HCC patient outcomes.
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