Related Experiment Video

Updated: Nov 9, 2025

Nasal Brushing Sampling and Processing Using Digital High Speed Ciliary Videomicroscopy – Adaptation for the COVID-19 Pandemic
09:03

Nasal Brushing Sampling and Processing Using Digital High Speed Ciliary Videomicroscopy – Adaptation for the COVID-19 Pandemic

Published on: November 7, 2020

5.1K

COVID-19 in Children: Respiratory Involvement and Some Differences With the Adults

Jenny Libeth Jurado Hernández1, Iván Francisco Álvarez Orozco2

  • 1Department of Pediatric Pulmonology, Fundación Neumológica Colombiana, Bogotá, Colombia.

Frontiers in Pediatrics
|April 15, 2021
PubMed

Insights

COVID-19 affects children differently than adults, with some experiencing severe respiratory issues like ARDS. Understanding these pediatric differences is key to better treatment and outcomes for children with COVID-19.

Area of Science:

  • Pediatric Pulmonology
  • Infectious Diseases
  • Virology

Background:

  • COVID-19 presents with varied respiratory symptoms in children, unlike the generally milder cases reported.
  • Increasing pediatric morbidity highlights the need to understand disease heterogeneity.
  • Severe respiratory complications include pneumonia and acute respiratory distress syndrome (ARDS).

Purpose of the Study:

  • To differentiate pediatric from adult COVID-19 respiratory compromise.
  • To enhance understanding of COVID-19's impact on the pediatric population.
  • To summarize key distinguishing features in pediatric COVID-19.

Main Methods:

  • Mini-review of existing literature.
  • Comparative analysis of pediatric versus adult COVID-19.
  • Focus on physiopathology, diagnosis, clinical presentation, severity, and treatment.

Main Results:

  • Children exhibit distinct physiopathological mechanisms and clinical presentations compared to adults.
  • Severity and progression of respiratory compromise vary significantly between pediatric and adult COVID-19 patients.
  • Diagnostic and therapeutic strategies require age-specific considerations.

Conclusions:

  • Understanding pediatric-specific COVID-19 mechanisms is crucial for improved management.
  • Tailored approaches to diagnosis, treatment, and control are necessary for the pediatric population.
  • Further research into pediatric COVID-19 is vital to mitigate its impact.

Keywords:
ARDSCOVID-19SARS-CoV-2childrenpneumoniarespiratory involvementrespiratory system

More Related Videos

Infection of Primary Nasal Epithelial Cells Grown at an Air-Liquid Interface to Characterize Human Coronavirus-Host Interactions09:02

Infection of Primary Nasal Epithelial Cells Grown at an Air-Liquid Interface to Characterize Human Coronavirus-Host Interactions

Published on: September 22, 2023

1.8K
An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection09:01

An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection

Published on: December 10, 2013

8.1K

Related Concept Videos

Common Respiratory Disorders01:31

Common Respiratory Disorders

Respiratory disorders, a prevalent health concern globally, are generally divided into two primary categories: upper and lower respiratory tract disorders. The categorization is based on the area of the respiratory system they affect.
Upper respiratory disorders impact the airways above the vocal cords, encompassing areas like the nose, sinuses, and throat. Various conditions fall under this category, including the common cold and allergic rhinitis. These disorders can stem from several causes,...
1.1K
COPD: Pathogenesis and Clinical Features01:20

COPD: Pathogenesis and Clinical Features

Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
1.5K
Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
466
Respiratory Capacities01:24

Respiratory Capacities

Respiratory capacities are crucial indicators of lung function, representing the maximum amount of air an individual's respiratory system can handle during various breathing phases.
One key metric is the Inspiratory Capacity (IC), which represents the maximum amount of air that can be inhaled with full effort. IC is calculated by summing the tidal volume and inspiratory reserve volume, typically ranging from 2.4 to 3.6 liters.
The Functional Residual Capacity (FRC) represents the air in the...
972
Pneumonia II: Pathophysiology01:29

Pneumonia II: Pathophysiology

The pathophysiology of pneumonia involves the following steps:
1.5K
Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
558