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Related Experiment Video

Updated: Nov 9, 2025

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
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SARS-CoV-2 docet.

Leopoldo Sarli1

  • 1Department of Medicine and Surgery, University of Parma, Italy. leopoldo.sarli@unipr.it.

Acta Bio-Medica : Atenei Parmensis
|April 15, 2021
PubMed
Summary
This summary is machine-generated.

The COVID-19 pandemic has evolved, with new variants spreading rapidly. Pregnant women face higher infection risks, and the virus can transmit to unborn children, highlighting the need for careful management.

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Area of Science:

  • Epidemiology
  • Infectious Diseases
  • Public Health

Background:

  • The COVID-19 pandemic, caused by SARS-CoV-2, has seen the emergence of more transmissible variants.
  • Asymptomatic and oligosymptomatic individuals can contribute to viral spread.
  • Pregnancy is associated with an increased risk of SARS-CoV-2 infection.

Discussion:

  • The "English" variant of SARS-CoV-2 demonstrates enhanced transmissibility.
  • Pregnant women may contract COVID-19 asymptomatically.
  • Vertical transmission of SARS-CoV-2 from mother to fetus is a significant concern.

Key Insights:

  • Pregnant women are at a higher risk of contracting COVID-19.
  • The SARS-CoV-2 infection can be transmitted to the unborn child.
  • Over-medicalization of low-risk pregnancies in the Italian female population is noted.

Outlook:

  • Further research is needed to understand the long-term effects of COVID-19 on pregnancy and newborns.
  • Public health strategies must adapt to the emergence of new SARS-CoV-2 variants.
  • Optimizing prenatal care for pregnant women during the pandemic is crucial.