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Simultaneous Bilateral Central Retinal Artery Occlusion following COVID-19 Infection
Maneesh M Bapaye1, Akshay Gopinathan Nair1,2,3, Charuta M Bapaye1
1Bapaye Eye Hospital, Nashik, Maharashtra, India.
Insights
Coronavirus-19 disease (COVID-19) can cause serious eye problems, including simultaneous bilateral retinal artery occlusion. This case highlights the potential for severe thrombotic events and long-term vision complications following COVID-19 infection.
Area of Science:
- Ophthalmology
- Hematology
- Infectious Diseases
Background:
- Coronavirus-19 disease (COVID-19) is linked to an increased risk of thrombotic events.
- Understanding the ocular manifestations of COVID-19 is crucial for patient management.
Observation:
- A 42-year-old male presented with sudden, bilateral vision loss post-COVID-19.
- Ophthalmic examination revealed bilateral retinal edema and cherry-red spots.
- Optical coherence tomography confirmed retinal thickening, with outer retinal layers intact.
Findings:
- The patient experienced simultaneous bilateral retinal artery occlusion.
- Coagulation profiles and tests for vasculitis were within normal limits.
- COVID-19 is associated with a hypercoagulable state, increasing thrombosis risk.
Implications:
- COVID-19 can lead to acquired thrombophilia and hyperinflammation.
- Ophthalmologists and physicians must recognize potential long-term thrombotic sequelae of COVID-19.
- Awareness of these risks is vital for timely diagnosis and intervention in COVID-19 patients.
Abstract:
Purpose: Coronavirus-19 disease (COVID-19) has been associated with a high risk of thrombotic complications. Here, we report the case of a patient who developed simultaneous bilateral retinal artery occlusion following COVID-19 infection.Case Report: A 42-year-old male with no systemic co-morbidities presented with sudden, painless loss of vision in both eyes. Fundoscopy showed retinal edema and cherry-red spots in both eyes. Fluorescein angiography showed reperfusion, absence of choroidal ischemia, and Optical Coherence Tomography showed thickened inner retinal layers suggestive of retinal edema and the outer retinal layers appeared intact. Blood investigations for vasculitis, coagulation profile, lipids, and homocysteine level were within normal limits.Conclusion: COVID-19 patients may develop a systemic coagulopathy and acquired thrombophilia characterized by a tendency for venous, arterial, and microvascular thrombosis. This hypercoagulable state is believed to be a hyperinflammatory response; physicians and ophthalmologists, alike, should be aware of these possible long-term sequelae.
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