Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Humps on young human and rabbit articular cartilage.

F N Ghadially, E M Moshurchak, I Thomas

    Journal of Anatomy
    |November 1, 1977
    PubMed
    Summary

    Articular cartilage surface topography differs between young and old individuals, with humps observed in the young and pits in the old. Ridges and undulations are likely artifacts, not normal features of healthy cartilage.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Achievement of Target Gain Larger than Unity in an Inertial Fusion Experiment.

    Physical review letters·2024
    Same author

    Lawson Criterion for Ignition Exceeded in an Inertial Fusion Experiment.

    Physical review letters·2022
    Same author

    Pitfalls in the diagnosis of death using neurological criteria.

    BJA education·2021
    Same author

    Current status of organ donation after brain death in the UK.

    Anaesthesia·2020
    Same author

    Vaccinating wild animals against rabies.

    Revue scientifique et technique (International Office of Epizootics)·2020
    Same author

    Diseases of wild animals transmissible to domestic animals.

    Revue scientifique et technique (International Office of Epizootics)·2020

    Area of Science:

    • Orthopedics
    • Biomaterials Science
    • Microscopy

    Background:

    • Articular cartilage is a vital tissue providing smooth joint articulation.
    • Understanding its surface topography is crucial for diagnosing and treating joint conditions.
    • Previous studies have shown variations in cartilage surface morphology with age.

    Purpose of the Study:

    • To investigate the surface topography of articular cartilage in young individuals using scanning electron microscopy.
    • To differentiate between normal surface features and potential artifacts in articular cartilage.

    Main Methods:

    • Scanning electron microscopy (SEM) was used to examine articular cartilage samples.
    • Samples were obtained from a 7-year-old human and rabbits of varying ages (1 and 2 months).
    • Different sample preparation methods, including air-drying and critical-point drying, were employed.

    Main Results:

    • Young individuals (7-year-old human, 1-month-old rabbits) exhibited humps on their articular cartilage surface.
    • Older individuals (implied from comparison) and 2-month-old rabbits showed pits, with intermediate features in the latter.
    • Ridges and undulations were observed in air-dried rabbit cartilage but were absent in critical-point dried specimens, suggesting they are artifacts.

    Conclusions:

    • Articular cartilage surface topography varies significantly with age.
    • Features like ridges and undulations are likely artifacts introduced during sample preparation, not inherent to normal articular cartilage.
    • SEM analysis, with careful consideration of preparation methods, is essential for accurate assessment of cartilage surface morphology.

    Related Experiment Videos