Treatment of Localized and Locally Advanced, High-Risk Prostate Cancer: A Report From the First Prostate Cancer...

Area of Science:

• Oncology
• Urology

Background:

• High-risk prostate cancer (PCa) poses unique challenges in developing countries.
• Limited resources necessitate tailored treatment and follow-up strategies.

Purpose of the Study:

• To generate and present survey results on critical issues in treating and following localized and locally advanced, high-risk prostate cancer (PCa).
• To focus specifically on the context of developing countries with limited resources.

Main Methods:

• A panel of 99 prostate cancer (PCa) experts developed over 300 survey questions.
• A larger panel of 99 international multidisciplinary cancer experts voted on 67 questions concerning treatment and follow-up for high-risk PCa in resource-limited settings.
• Consensus was defined as 75% agreement; recommendations prioritized cost-effectiveness and accessibility.

Main Results:

• Survey results and expert opinions were tabulated in real-time.
• Recommendations were based on panelist consensus, not solely on literature review.
• Consideration was given to cost-effectiveness and accessibility of therapies in resource-limited areas.

Conclusions:

• The presented voting results and recommendations can guide physicians managing high-risk prostate cancer (PCa) in resource-limited settings.
• This article serves as a crucial reference point in the absence of defined treatment guidelines for prostate cancer (PCa) in developing countries.