Related Experiment Video
Updated: Nov 9, 2025

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System
Published on: October 16, 2013
Endoscopic characteristics influencing postpolypectomy bleeding in 1147 consecutive pedunculated colonic polyps: a
Teppei Tagawa1, Masayoshi Yamada2, Takeyoshi Minagawa3
1Endoscopy Division, National Cancer Center Hospital, Tokyo, Japan; Department of Medicine, Division of Gastroenterology, Showa University School of Medicine, Tokyo, Japan.
Postpolypectomy bleeding risk factors for pedunculated colonic polyps were identified. Wider stalks increase immediate bleeding risk, while prophylactic clipping and stalk injection raise delayed bleeding risk.
Area of Science:
- Gastroenterology
- Endoscopic Surgery
- Colorectal Cancer Prevention
Background:
- Postpolypectomy bleeding is a common complication, particularly with pedunculated polyps.
- Identifying endoscopic characteristics that influence bleeding is crucial for patient safety.
Purpose of the Study:
- To clarify endoscopic factors associated with postpolypectomy bleeding in pedunculated colonic polyps.
- To inform strategies for reducing bleeding complications during colon polyp removal.
Main Methods:
- Retrospective review of 1147 pedunculated colonic polyp resections across 5 Japanese institutions.
- Analysis of clinical data including polyp characteristics, prophylactic measures, and bleeding events (immediate and delayed).
Main Results:
- Stalk width ≥6 mm was a significant risk factor for immediate bleeding (OR 1.9).
- Prophylactic endoloop use inhibited immediate bleeding for polyps ≥15 mm (OR 0.17).
- Prophylactic clipping (OR 4.2) and stalk injection (OR 4.0) increased delayed bleeding risk.
Conclusions:
- Simple resection with coagulation mode is suggested for pedunculated polyps to minimize delayed bleeding.
- Prophylactic endoloop use is effective in preventing immediate bleeding for larger polyps (≥15 mm).
Related Concept Videos
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Endoscopic Procedures II: Colonoscopy
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:
Assessment of the Rectum and Anus
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...

