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Published on: May 17, 2019
[Analysis for the breast cancer screening among urban population in Hebei province, 2018-2019]
1Cancer Institute, The Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China.
Insights
The Cancer Screening Program in Urban China (CanSPUC) identified breast cancer in 4.26% of high-risk women. Combined mammography and ultrasound screening proved most effective for early detection.
Area of Science:
- Oncology
- Public Health
- Medical Imaging
Background:
- Breast cancer screening is crucial for early detection and improved outcomes.
- The Cancer Screening Program in Urban China (CanSPUC) aims to reduce breast cancer mortality in high-risk populations.
- Understanding screening effectiveness across different demographics and modalities is essential.
Purpose of the Study:
- To evaluate the effectiveness of the CanSPUC in Hebei Province.
- To determine breast cancer and suspicious positive rates within a high-risk population.
- To compare the diagnostic yield of different imaging modalities for breast cancer detection.
Main Methods:
- Screening of 3,453 high-risk individuals aged 53.94±8.00 from 2018-2019.
- Analysis of breast cancer positive and suspicious positive cases.
- Comparison of detection rates using ultrasound alone, mammography alone, and combined mammography and ultrasound.
Main Results:
- A breast cancer positive rate of 4.26% and a suspicious positive rate of 19.87% were observed.
- The 45-49 age group had the highest suspicious positive rate (28.32%), while the over 70 group had the highest positive rate (7.32%).
- Combined mammography and ultrasound yielded a significantly higher positive detection rate (5.16%) compared to ultrasound (2.46%) or mammography (3.06%) alone (P<0.001).
Conclusions:
- The CanSPUC identified a notable proportion of breast cancer cases in a high-risk urban Chinese population.
- Screening effectiveness varied by age group, highlighting the need for tailored approaches.
- Combined mammography and ultrasound represent a superior screening strategy for enhancing breast cancer detection rates.
Abstract:
From 2018 to 2019, 3 453 cases of high-risk population were screened by the Cancer Screening Program in Urban China (CanSPUC) in Hebei Province, with the age of (53.94±8.00). 147 and 686 cases of breast cancer positive and suspicious positive patients were found, with the positive rate and suspicious positive rate of 4.26% and 19.87% respectively. The suspicious positive rate of 45-49 years old age group was the highest (28.32%), and the positive rate of over 70 years old age group was the highest (7.32%). The positive detection rate of mammography combined with ultrasound was 5.16%, which was higher than that of ultrasound alone (2.46%) (χ²=30.28,P<0.001) or mammography alone (3.06%) (χ²=14.56,P<0.001).
