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Updated: Nov 9, 2025

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Published on: January 27, 2018
Laryngeal Dystonia: Multidisciplinary Update on Terminology, Pathophysiology, and Research Priorities
Kristina Simonyan1, Julie Barkmeier-Kraemer2, Andrew Blitzer2
1From the Department of Otolaryngology-Head and Neck Surgery (K.S.), Harvard Medical School and Massachusetts Eye and Ear, Boston, MA, Department of Neurology (K.S., L.J.O., N.S.), Massachusetts General Hospital, Boston, MA; Division of Otolaryngology (J.B.-K.), University of Utah, Salt Lake City, UT; New York Center for Voice and Swallowing Disorders and Department of Neurology (A.B.), Icahn School of Medicine at Mount Sinai, New York, NY; Human Motor Control Section (M.H.), National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD; Department of Otolaryngology-Head and Neck Surgery (J.H.), University of California San Francisco, San Francisco, CA; School of Rehabilitation and Health Sciences (T.J.K.), Massachusetts General Hospital Institute of Health Professions, Boston, MA; Department of Otolaryngology-Head and Neck Surgery (M.J.P.), Columbia University Irving Medical Center, New York, NY; Department of Neurosurgery (R.M.R.), Massachusetts General Hospital, Boston, MA; and Department of Communication Disorders (K.T.), Brigham Young University, Provo, UT. kristina_simonyan@meei.harvard.edu.
Experts recommend focusing research on laryngeal dystonia (LD) to find biomarkers for diagnosis and targeted therapies. Collaborative efforts are key to advancing understanding and treatment of this rare neurological disorder.
Area of Science:
- Neurology
- Neuroscience
Background:
- Laryngeal dystonia (LD), previously termed spasmodic dysphonia, is a multifactorial, heterogeneous disorder.
- Its etiology is unknown, but pathophysiology likely involves disorganized brain networks.
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