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Publisher Correction: A single-dose mRNA vaccine provides a long-term protection for hACE2 transgenic mice from

Qingrui Huang1, Kai Ji1,2, Siyu Tian1,2

  • 1CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.

Nature Communications
|April 16, 2021
PubMed
Abstract

No abstract available in PubMed .

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During most eukaryotic translation processes, the small 40S ribosome subunit scans an mRNA from its 5' end until it encounters the first start AUG codon. The large 60S ribosomal subunit then joins the smaller one to initiate protein synthesis. The location of the translation initiation is largely determined by the nucleotides near the start codon as there may be multiple translation initiation sites present on the mRNA.  Marilyn Kozak discovered that the sequence RCCAUGG (where R stands for...

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