Related Experiment Video
Updated: Nov 9, 2025

08:10
Diagnosing Pulmonary Tuberculosis with the Xpert MTB/RIF Test
Published on: April 9, 2012
81.4K
Tuberculosis among Migrant Populations in Sicily: A Field Report
Tullio Prestileo1,2, Giuseppe Pipitone1,3, Adriana Sanfilippo1
1Infectious Disease Unit & Centre for Migration and Health, ARNAS Civico Di Cristina Benfratelli Hospital, Palermo, Italy.
Journal of Tropical Medicine
|April 16, 2021
Summary
Tuberculosis screening in migrants found a 13.5% infection rate, with 1.6% active tuberculosis. Early detection through screening is crucial for managing TB in vulnerable populations.
Area of Science:
- Public Health
- Infectious Diseases
- Epidemiology
Background:
- Tuberculosis (TB) disproportionately affects vulnerable populations, including migrants in the European Union.
- A study assessed TB and latent TB infection (LTBI) prevalence among migrants in western Sicily between 2014-2017.
- The ITaCA network hosted migrants in 41 reception centers for this evaluation.
Purpose of the Study:
- To estimate the frequency of tuberculosis and latent tuberculosis infection (LTBI) among migrants in western Sicily.
- To identify the prevalence of active TB and LTBI within this specific migrant population.
Main Methods:
- Screening involved physical examination, Tuberculin Skin Test (TST), and Interferon-Gamma Release Assay (IGRA) on 3,710 migrants.
- Screening occurred 4-8 weeks post-arrival in Sicily.
- Positive screening results led to chest X-rays and smear examinations to confirm active TB or LTBI.
Main Results:
- Tuberculosis infection was diagnosed in 13.5% (501/3,710) of migrants.
- Latent TB infection (LTBI) was identified in 11.8% (440/3,710) and active TB in 1.6% (61/3,710).
- Pulmonary TB was the most common form of active TB (59 cases), with no drug-resistant cases observed.
Conclusions:
- Tuberculosis screening is essential for the early diagnosis and treatment of TB in migrant populations.
- Prompt identification and management can mitigate TB transmission within reception centers and the wider community.
Related Concept Videos
Pulmonary Tuberculosis IV
257
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
257
Pulmonary Tuberculosis I
451
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
451
Pulmonary Tuberculosis V
305
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
305
Pulmonary Tuberculosis II
802
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
802
Pulmonary Tuberculosis III
568
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
568

