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An Aggressive Liposarcoma Presenting as a Perforated Colon Mass
Rebecca Innes1, Sylvester Paulasir2, Lesley Combs2
1Surgery, Henry Ford Health System, Jackson, USA.
Cureus
|April 16, 2021
Summary
Dedifferentiated liposarcoma (DDLS) is a rare, aggressive sarcoma that can involve the colon. This case highlights rapid progression and metastasis of DDLS in the cecum.
Area of Science:
- Oncology
- Surgical Pathology
Background:
- Dedifferentiated liposarcoma (DDLS) typically originates in the retroperitoneum.
- Colonic involvement by DDLS is exceptionally rare, with limited documented cases.
Observation:
- A case of DDLS presenting as a perforated cecal mass is described.
- Rapid tumor development over six months was noted via computed tomography (CT).
Findings:
- The patient underwent right hemicolectomy with en bloc resection for the perforated colon mass.
- Despite no initial metastatic disease, widespread metastases (liver, lungs, peritoneum) were evident at three-month follow-up.
Implications:
- This case underscores the aggressive potential and rapid progression of rare colonic DDLS.
- Highlights the importance of early detection and management of unusual gastrointestinal sarcomas.
