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Updated: Jul 23, 2026

A Protocol for Using Gene Set Enrichment Analysis to Identify the Appropriate Animal Model for Translational Research
Published on: August 16, 2017
GSEAplot: A Package for Customizing Gene Set Enrichment Analysis in R
Sarah E Innis1, Kelsie Reinaltt1, Mete Civelek1,2
1Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, USA.
Abstract:
Gene Set Enrichment Analysis (GSEA) is used to identify differentially expressed gene sets that are enriched for annotated biological functions. The existing GSEA R code is not in the form of a flexible package with analysis and plotting customization options, and the results produced are not generated in the form of R objects. In this study, we introduce the GSEAplot R package with novel functionality for saving relevant information from the analysis to the current R workspace, and we introduce the ability to customize plots and databases. The GSEAplot package provides a novel utility that facilitates the implementation of GSEA R-based in genomics analysis pipelines.

