Related Experiment Video
Updated: Nov 9, 2025

Long-term Behavioral and Reproductive Consequences of Embryonic Exposure to Low-dose Toxicants
Published on: March 6, 2018
Exposure to endocrine disruptors and risk of breast cancer: A systematic review
Priscilla Roberta Silva Rocha1, Valdiane Dutra Oliveira2, Christiane Inocêncio Vasques3
1Faculty of Ceilândia, University of Brasília, Campus Universitário s/n, Metropolitan Center, Brasília, DF, 72220-275, Brazil.
Aim:
The aim of this study was to investigate the association between human exposure to endocrine disruptors (EDs) and the risk of breast cancer.
Methods:
This was a systematic review conducted by searching Cochrane Library, LILACS, Livivo, PubMed, and Science Direct. Observational studies addressing the association between exposure to EDs and breast cancer risk in adults were included. Risk of bias was assessed using the National Toxicology Program's Office of Health Assessment Translation tool.
Results:
a total of 37 studies were included. Most studies reported that exposure to organochlorine pesticides, phthalates, heavy metals, and polycyclic aromatic hydrocarbons was associated with increased breast cancer risk.
Conclusion:
qualitative analysis of observational studies indicates that human exposure to EDs is associated with increased breast cancer risk. Additional studies are needed to determine whether this association is causal.
More Related Videos
Related Concept Videos
Disorders of the Female Reproductive System
What is the Endocrine System?
Cancer Prevention
Some...
Psychoneuroimmunology: Diabetes and Cancer
Endocrine Signaling
Types of Toxins
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...

