Asthma does not influence the severity of COVID-19: a meta-analysis

Ting Wu1, Pengyi Yu1, Yuanxia Li2

  • 1Department of Otorhinolaryngology Head and Neck Surgery, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong, China.

Insights

Asthma does not increase the risk of severe coronavirus disease-2019 (COVID-19). This meta-analysis found no significant association between asthma and severe COVID-19 outcomes.

Area of Science:

  • Pulmonary Medicine
  • Infectious Diseases
  • Epidemiology

Background:

  • Previous studies suggest a correlation between COVID-19 and asthma.
  • Data on asthma as a COVID-19 risk factor and its prevalence in COVID-19 cases remain limited.

Purpose of the Study:

  • To analyze the association between COVID-19 and asthma.
  • To determine if asthma is a risk factor for severe COVID-19.
  • To assess the prevalence of asthma in COVID-19 patients.

Main Methods:

  • Systematic literature search of PubMed, Embase, and Web of Science databases (Jan 1 - Aug 28, 2020).
  • Inclusion of 18 studies reporting epidemiological and clinical features of COVID-19 and asthma prevalence.
  • Meta-analysis of pooled data.

Main Results:

  • The pooled prevalence of asthma in COVID-19 cases was 0.08 (95% CI, 0.06-0.11).
  • Asthma was not found to increase the risk of developing severe COVID-19 (OR 1.04, 95% CI 0.75-1.46).
  • No significant difference in asthma incidence with age was observed in COVID-19 infections.

Conclusions:

  • Asthma is not a significant risk factor for the development of severe COVID-19.
  • The findings contribute to understanding the interplay between respiratory conditions and severe viral infections.
Abstract

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