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Acute Bilateral Fixed Mydriasis Caused by Lupini Bean Intoxication
Corinne Lahoud1, Najib-Georges Hanna2, Alexandre Jalkh3
1Faculty of Medicine and Medical Sciences, Holy Spirit University of Kaslik, Usek, Lebanon; Eye and Ear Hospital International, Naccache, Lebanon.
Wilderness & Environmental Medicine
|April 17, 2021
Summary
Improperly prepared lupini beans can cause anticholinergic toxicity. A case study highlights symptoms like dilated pupils and dry mouth, emphasizing the need for correct bean preparation.
Area of Science:
- Toxicology
- Pharmacology
- Botany
Background:
- Lupini beans (genus Lupinus) are widely consumed legumes.
- Rich in alkaloids, they possess a characteristic bitter taste.
- Certain alkaloids can induce anticholinergic effects.
Observation:
- A 50-year-old woman presented with bilateral mydriasis, dry mouth, and anxiety.
- She had consumed partially debittered lupini beans hours prior.
- Other examinations were normal.
Findings:
- The patient's symptoms are consistent with anticholinergic syndrome.
- The adverse effects were attributed to improperly prepared lupini beans.
- Symptoms resolved spontaneously within 12 hours.
Implications:
- Highlights the potential toxicity of improperly prepared lupini beans.
- Underscores the importance of proper debittering processes for lupine consumption.
- Informs clinical recognition of anticholinergic syndrome from dietary sources.
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