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Updated: Nov 9, 2025

A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma
Published on: September 30, 2021
Therapies for hepatocellular carcinoma: overview, clinical indications, and comparative outcome evaluation. Part two:
Joseph H Yacoub1,2, David Mauro3, Andrew Moon3
1Department of Radiology, Georgetown University, Washington DC, USA. joeyacoub@gmail.com.
Abstract:
Locoregional therapies can be offered to hepatocellular carcinoma patients as a bridge to transplant, to downstage disease burden for transplant eligibility, or for disease control to prolong survival. Systemic therapies also play a large role in HCC treatment, occasionally in conjunction with other methods. This manuscript reviews the various treatment options for HCC with a historically noncurative intent.
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