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Localized bullous pemphigoid after knee replacement surgery.
Daniel Wenzel, Rebecca Droms, Jessica St John
1Department of Dermatology, University of Massachusetts Medical School, Worcester, MA. nikki.levin@umassmemorial.org.
Dermatology Online Journal
|April 18, 2021
Summary
Localized bullous pemphigoid (BP) can mimic other skin conditions, making diagnosis challenging. This case highlights how surgical procedures may trigger localized BP, emphasizing the need for prompt recognition and treatment.
Area of Science:
- Dermatology
- Immunodermatology
Background:
- Bullous pemphigoid (BP) is an autoimmune blistering disease typically affecting the elderly.
- Localized bullous pemphigoid is an uncommon variant that poses diagnostic challenges due to its varied presentation.
Observation:
- A 57-year-old woman presented with intensely itchy, tense blisters on her anterior right knee.
- The blisters were located over a surgical scar from a knee replacement performed six months prior.
Findings:
- The clinical presentation was consistent with localized bullous pemphigoid.
- The surgical procedure was identified as a potential trigger for the localized bullous pemphigoid.
Implications:
- Early diagnosis of localized bullous pemphigoid is crucial for effective management.
- Surgical interventions may represent a novel trigger for bullous pemphigoid development.
