Prognostic implications of thyroid hormone alterations in acute coronary syndrome-A systematic review
Priyadarshini Arambam1, Upendra Kaul2, Priya Ranjan3
1Academics & Research Department, Batra Heart Center, Batra Hospital and Medical Research Center, New Delhi, India; Labratory of Disease Dynamics and Molecular Epidemiology, Amity Institute of Public Health, Amity University Campus, Noida, Uttar Pradesh, India.
Abstract:
There is considerable association of thyroid function and the cardiovascular system during various acute systemic illnesses. It is well established that the normal thyroid homeostasis is known to alter in disease states including the acute coronary syndromes (ACS). Abnormal thyroid hormonal status has been shown to be related to worse outcomes and prognosis. This review focuses on the relationship of alterations in thyroid function and its influence on the pathophysiological mechanisms and cardiovascular hemodynamics in ACS and based upon the literature, summarises all the existing evidence to this date on this subject. The data largely points out that low levels of triiodothyronine (T3) levels seen in ACS might be useful in prognosticating the outcomes of ACS.
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Functions of Thyroid Hormones
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
