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Related Experiment Videos

[Multifocal epileptic crises following mumps].

D Parain1, J Boulloche

  • 1Service d'explorations neurologiques, CHU Hôpital Charles-Nicolle, Rouen, France.

Neurophysiologie Clinique = Clinical Neurophysiology
|April 1, 1988
PubMed
Summary
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Mumps encephalitis can cause multifocal seizures in adolescents, presenting with varied symptoms like facial myoclonus and visual hallucinations. Prompt treatment led to seizure resolution and no relapse, highlighting the importance of identifying viral causes.

Area of Science:

  • Neurology
  • Pediatrics
  • Infectious Diseases

Background:

  • Epilepsy in adolescents can stem from various causes, including infectious agents.
  • Mumps virus is a known cause of central nervous system infections.

Observation:

  • A 15-year-old presented with new-onset multifocal seizures, including facial myoclonus, sensory seizures with secondary generalization, and visual hallucinations.
  • Electroencephalogram (EEG) showed abnormalities in the parietal and occipital lobes during sensory and visual seizures.
  • Cerebrospinal fluid (CSF) analysis revealed pleocytosis, and serology confirmed recent mumps infection.

Findings:

  • The patient experienced frequent, diverse seizures attributed to mumps encephalitis.
  • Initial anticonvulsant therapy was ineffective, but seizures resolved spontaneously within a month.

Related Experiment Videos

  • Complete seizure remission was observed during a one-year follow-up after drug discontinuation.
  • Implications:

    • This case underscores mumps encephalitis as a potential cause of new-onset multifocal epilepsy in adolescents.
    • Early diagnosis and supportive care are crucial for managing seizures associated with viral encephalitis.
    • The findings suggest that mumps encephalitis can lead to transient, severe neurological manifestations.