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Related Experiment Video

Updated: Nov 8, 2025

Therapy Interventions for Upper Limb Amputees Undergoing Selective Nerve Transfers
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Psychiatric Disease after Isolated Traumatic Upper Extremity Amputation.

Shirley Shue1, Yuewei Wu-Fienberg2, Kyle J Chepla2

  • 1Case Western Reserve University School of Medicine, Cleveland, Ohio, United States.

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|April 19, 2021
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Psychiatric conditions like depression and PTSD are common after traumatic upper extremity amputation in civilians. No specific risk factors were identified, highlighting the need for surgeon awareness.

Keywords:
amputationfarmprevalencepsychiatrictraumatic

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Area of Science:

  • Orthopedics
  • Psychiatry
  • Rehabilitation Medicine

Background:

  • Traumatic limb loss significantly impacts patient recovery and quality of life.
  • Psychiatric conditions are a known complication following amputation, affecting rehabilitation outcomes.
  • Understanding the prevalence and risk factors for psychiatric disease after upper extremity amputation is crucial for patient care.

Purpose of the Study:

  • To determine the prevalence of psychiatric disease in civilians following traumatic upper extremity amputation.
  • To identify potential risk factors associated with the development of psychiatric conditions in this patient population.

Main Methods:

  • Retrospective review of patient demographics, injury details, amputation level, and prosthetic use.
  • Analysis of International Statistical Classification of Diseases and Related Health Problems, 10th revision (ICD-10) diagnosed psychiatric conditions and treatment duration.
  • Statistical analysis including descriptive statistics, Fisher's exact test, and relative risk assessment.

Main Results:

  • 67.4% of patients (31 out of 46) had at least one diagnosed psychiatric condition.
  • Major depressive disorder (14 patients) and posttraumatic stress disorder (11 patients) were the most prevalent conditions.
  • No statistically significant correlation was found between psychiatric illness and factors such as gender, age, time since injury, employment, workers' compensation status, hand affected, or amputation level.

Conclusions:

  • The prevalence of depression and anxiety after traumatic upper extremity amputation in civilians mirrors rates seen after combat injuries.
  • Despite no identified statistically significant risk factors in this study, upper extremity surgeons must recognize the high incidence of psychiatric disease.
  • Awareness and screening for psychiatric conditions are essential for optimizing rehabilitation and quality of life in patients with traumatic upper extremity amputations.