SeBioGraph: Semi-supervised Deep Learning for the Graph via Sustainable Knowledge Transfer
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Updated: Nov 8, 2025

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
1School of Architecture and Urban Planning, Chongqing University, Chongqing, China.
Abstract:
Semi-supervised deep learning for the biomedical graph and advanced manufacturing graph is rapidly becoming an important topic in both academia and industry. Many existing types of research focus on semi-supervised link prediction and node classification, as well as the application of these methods in sustainable development and advanced manufacturing. To date, most manufacturing graph neural networks are mainly evaluated on social and information networks, which improve the quality of network representation y integrating neighbor node descriptions. However, previous methods have not yet been comprehensively studied on biomedical networks. Traditional techniques fail to achieve satisfying results, especially when labeled nodes are deficient in number. In this paper, a new semi-supervised deep learning method for the biomedical graph via sustainable knowledge transfer called SeBioGraph is proposed. In SeBioGraph, both node embedding and graph-specific prototype embedding are utilized as transferable metric space characterized. By incorporating prior knowledge learned from auxiliary graphs, SeBioGraph further promotes the performance of the target graph. Experimental results on the two-class node classification tasks and three-class link prediction tasks demonstrate that the SeBioGraph realizes state-of-the-art results. Finally, the method is thoroughly evaluated.
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