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Marantic Endocarditis Associated with COVID-19: A Rare Case Report of a Potentially Deadly Disease

Kok Hoe Chan1, Ormena Joseph1, Eyad Ahmed1

  • 1Department of Medical Education, Saint Michael's Medical Centre, New York Medical College, Newark, New Jersey, USA.

European Journal of Case Reports in Internal Medicine
|April 19, 2021
PubMed

Insights

Coronavirus disease 2019 (COVID-19) can cause a hypercoagulable state, leading to rare complications like non-bacterial thrombotic endocarditis (NBTE). This case highlights the importance of recognizing this association in patients with COVID-19.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Hematology

Background:

  • Coronavirus disease 2019 (COVID-19) is a global pandemic associated with significant morbidity and mortality.
  • A hypercoagulable state is a recognized complication of COVID-19, contributing to poor prognosis.
  • Marantic endocarditis (non-bacterial thrombotic endocarditis, NBTE) involves sterile cardiac valve vegetations due to fibrin and platelet deposition, often linked to hypercoagulable states.

Purpose of the Study:

  • To report a rare case of non-bacterial thrombotic endocarditis (NBTE) in a patient with Coronavirus disease 2019 (COVID-19).
  • To increase physician awareness of the potential association between COVID-19 and NBTE.

Main Methods:

  • Case report detailing a unique clinical presentation.
  • Review of relevant medical literature.

Main Results:

  • A patient with COVID-19 presented with non-bacterial thrombotic endocarditis (NBTE).
  • This represents one of the few documented cases of NBTE associated with COVID-19.

Conclusions:

  • COVID-19 infection can lead to a hypercoagulable state.
  • Non-bacterial thrombotic endocarditis (NBTE) is a rare but potential complication of COVID-19.
  • Increased physician awareness is crucial for identifying this association.

Keywords:
COVID-19COVID-19 associated coagulopathyMarantic endocarditishypercoagulable statenon-bacterial thrombotic endocarditis

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