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Liprin-α-Mediated Assemblies and Their Roles in Synapse Formation

Xingqiao Xie1,2, Mingfu Liang1, Cong Yu1,3

  • 1Department of Biology, Southern University of Science and Technology, Shenzhen, China.

Frontiers in Cell and Developmental Biology
|April 19, 2021
PubMed
Summary

Liprin-alpha proteins act as master scaffolds, organizing protein complexes essential for synapse formation and function in the brain. Recent structural and biochemical studies are revealing the molecular mechanisms behind these crucial synaptic assemblies.

Keywords:
LLPSSYD2coiled coilpresynaptic active zoneprotein structureprotein–protein interactionscaffold protein

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