Sudden Death and Coronary Artery Anomalies
Stefania Rizzo1, Monica De Gaspari1, Carla Frescura1
1Cardiovascular Pathology, Azienda Ospedaliera, Department of Cardiac, Thoracic and Vascular Sciences, and Public Health, University of Padua, Padua, Italy.
Frontiers in Cardiovascular Medicine
|April 19, 2021
Summary
Congenital coronary artery anomalies (CAA) can be asymptomatic or cause sudden cardiac death (SCD), especially in young people and athletes. Understanding normal coronary artery anatomy and CAA pathology is crucial for risk assessment.
Area of Science:
- Cardiology
- Congenital Heart Disease
- Sudden Cardiac Death
Background:
- Congenital coronary artery anomalies (CAA) are present from birth, presenting diverse clinical outcomes.
- CAA can be asymptomatic incidental findings or lead to severe ischemia and sudden cardiac death (SCD).
Purpose of the Study:
- To discuss normal coronary artery (CA) anatomy.
- To review the pathology of CAA with a high risk for SCD.
- To present findings from SCD victims in young individuals (<40 years) and athletes.
Main Methods:
- Literature review of normal CA anatomy and CAA pathology.
- Analysis of case data from SCD victims.
Main Results:
- CAA encompasses a spectrum of malformations with varied severity.
- SCD can be the initial presentation of CAA, particularly in young individuals and athletes.
Conclusions:
- CAA poses a significant risk for SCD, especially in specific demographics.
- Knowledge of CA anatomy and CAA pathology is vital for identifying at-risk individuals.
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