Contemporary treatment of May-Thurner Syndrome

Arash Fereydooni1, Jordan R Stern2

  • 1Division of Vascular and Endovascular Surgery, Department of Surgery, Stanford University Medical Center, Stanford, CA, USA.

Insights

May-Thurner Syndrome, caused by left iliac vein compression, can lead to leg swelling or deep vein thrombosis. Iliocaval stenting is a standard treatment with good outcomes.

Area of Science:

  • Vascular Surgery
  • Diagnostic Imaging
  • Venous Disease Management

Background:

  • May-Thurner Syndrome arises from left common iliac vein compression by the right common iliac artery.
  • This compression can cause venous outflow obstruction, leading to unilateral leg swelling or deep vein thrombosis.

Purpose of the Study:

  • To review the pathophysiology of May-Thurner Syndrome.
  • To discuss diagnostic modalities and treatment options for May-Thurner Syndrome.

Main Methods:

  • Review of existing literature on May-Thurner Syndrome.
  • Analysis of diagnostic techniques including ultrasound, CT venography, MR venography, and intravascular ultrasound.
  • Evaluation of treatment strategies, focusing on iliac vein stenting.

Main Results:

  • May-Thurner Syndrome diagnosis relies on clinical presentation and imaging.
  • Venography with intravascular ultrasound is optimal for assessing iliac vein compression severity.
  • Iliocaval stenting demonstrates promising patency rates and clinical outcomes for treatment.

Conclusions:

  • Understanding May-Thurner Syndrome's pathophysiology is crucial for diagnosis and management.
  • A combination of diagnostic tools aids in identifying and assessing the severity of venous compression.
  • Iliocaval stenting is an effective, standard treatment for hemodynamically significant May-Thurner Syndrome.

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