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Updated: Nov 8, 2025

Scale-up Chemical Synthesis of Thermally-activated Delayed Fluorescence Emitters Based on the Dibenzothiophene-S,S-Dioxide Core
Published on: October 24, 2017
Achieving high singlet-oxygen generation by applying the heavy-atom effect to thermally activated delayed fluorescent
Ya-Fang Xiao1, Jia-Xiong Chen1, Wen-Cheng Chen2
1Center of Super-Diamond and Advanced Films (COSDAF) and Department of Chemistry, City University of Hong Kong, Hong Kong, 999077, P. R. China. apcslee@cityu.edu.hk and Joint Laboratory of Nano-Organic Functional Materials and Devices (TIPC and CityU), City University of Hong Kong, Kowloon, Hong Kong SAR, P. R. China.
Abstract:
A bromine-substituted thermally activated delayed fluorescent (TADF) molecule AQCzBr2 is designed with both small singlet-triplet splitting (ΔEST) and increased spin-orbit coupling (SOC) to boost intersystem crossing (ISC) for singlet oxygen generation. AQCzBr2 nanoparticles (NPs) demonstrate high productivity of singlet oxygen generation (ΦΔ = 0.91) which allows highly efficient photodynamic therapy toward cancer cells.
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