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Updated: Nov 8, 2025

Heterogeneous Removal of Water-Soluble Ruthenium Olefin Metathesis Catalyst from Aqueous Media Via Host-Guest Interaction
Published on: August 23, 2018
Light-Driven gem Hydrogenation: An Orthogonal Entry into "Second-Generation" Ruthenium Carbene Catalysts for Olefin
Raphael J Zachmann1, Alois Fürstner1
1Max-Planck-Institut für Kohlenforschung, 45470, Mülheim/Ruhr, Germany.
Abstract:
The newly discovered light-driven gem hydrogenation of alkynes opens an unconventional yet efficient entry into five-coordinate Grubbs-type ruthenium carbene complexes with cis-disposed chloride ligands. Representatives of this class featuring a chelate substructure formed by an iodo-substituted benzylidene unit react with (substituted) 2-isopropoxystyrene to give prototypical "second-generation" Grubbs-Hoveyda complexes for olefin metathesis. The new approach to this venerable catalyst family is safe and versatile as it uses a triple bond rather than phenyldiazomethane as the ultimate carbene source and does not require any sacrificial phosphines.
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